Hyaluronic Acid: Skin Matrix Health is not just About Proteins.



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If the fibrous middle layer of the skin is taken at and all cells are removed from it we can see the skin matrix. It is responsible for integrity, resilience & stability of the skin. Degradation of skin matrix leads to development of wrinkles and other signs of skin aging collagen and elastin are main structural proteins vital for health & youthfulness of the skin. Just like steel beams and bars are necessary but insufficient for building a skyscraper these structural proteins alone can not maintain the health of skin matrix. It also needs appropriate fillers, holding moisture and enhanced barrier function. Main skin fillers are glycans- glucose based polymers that include glycosaminogly cause and proteolysis. Hyaluronic Acid (a.k.a, hyaluronan or hyaluronate) is the most important glycan necessary for skin rejuvenation.

Functions of Hyaluronic acid throughout the body specially in skin physiology

1. It holds moisture.

2. It increases viscosity & reduces permeability of extra Cellular fluid.

3. It contributes to mechanical resilience & suppleness of skin.

4. It regulates repairs of tissues.

5. It regulates movement and growth of cells.

6. It controls immune and inflammatory responses.

Physiological effects of hyaluronic acid

The physiological effects of hyaluronic acid depend largely on the size (molecular weight) of its chain. Small H.A. molecules (weighing less than about 2000 DA) appear to check early would healing and activates various types of immune cells and inflammatory responses. Predominance of large H.A. molecules send a singular that skin is intact and does not require repair.

EDITOR’S NOTE ON HYALURONIC ACID STIMULATION

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Hyaluronic Acid & aging - the skin content of hyaluronic acid decreases with age and leads to loss of moisture. Skin becomes thinner and less supple. Loss of H.A. many also impair skins ability to repair itself and may affect other skin matrix components.

Can we boost hyaluronic acid in our skin?

The problem of checking decline of H.A. in skin is an important issue in skin care. Unfortunately tell now there is no simple, inexpensive and effective way to pressure of restore H.A. levels in skin.

But certain options are available and hold promise for the future.

i). Topical hyaluronic acid in the from of given & serves are widely available but their usefulness is limited.

ii) H.A. can provide effective moisture on surface of the skin either alone or with other moisturizing in gradients but in further research.

iii) Since large & medium hyaluronic acid molecules can not perpetrate the skin significantly, one alternative is to deliver H.A. via injection. This may improve locoweed imperfections e,g wrinkles, furrow, depressed scats etc. but an not revitalize the skin over all.

October 14, 2008 | Filed Under Anti aging skin treatments

 

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